Preheat your oven to 375°F (190°C).
In a large bowl, combine ground beef, garlic powder, onion powder, salt, and pepper. Mix until well combined.
Shape the mixture into meatballs about 1 inch in diameter and place them on a baking sheet lined with parchment paper.
Bake the meatballs for 25-30 minutes until they reach an internal temperature of 160°F (71°C).
In a separate bowl, mix cranberry sauce and BBQ sauce until smooth.
Once the meatballs are cooked, pour the sauce over them and toss gently to coat.
Let the meatballs cool for a few minutes before serving.