Preheat your oven to 350°F (175°C).
Grease a 9x5-inch loaf pan with butter or cooking spray, or line it with parchment paper.
In a large mixing bowl, whisk together the gluten-free flour, sugar, baking powder, baking soda, and salt.
In another bowl, mix the melted butter, eggs, orange juice, orange zest, and vanilla extract until smooth.
Pour the wet ingredients into the dry ingredients and stir until just combined. Fold in the chopped cranberries.
Pour the batter into the prepared loaf pan and smooth the top.
Bake for 55-60 minutes, or until a toothpick inserted into the center comes out clean.
Allow the bread to cool in the pan for 10 minutes, then transfer to a wire rack to cool completely.